Allergic Reactions (Rare): Although rare, some individuals can have an allergic reaction to the injection, ranging from a rash or itching to more severe symptoms like swelling of the face, tongue, or throat, dizziness, or difficulty breathing
This homeostatic mechanism has been a key focus in wound healing and dermatological research models
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DOI: 10.1158/1055-9965.EPI-17-1136 Morales-Gutierrez J et al, "Toxicity induced by multiple high doses of vitamin B 12 during pernicious anemia treatment: a case report." Clinical Toxicology, Feb
The absorption rate from B12 injections is higher than it is from taking supplements, Allen says, which is why it can cause side effects